Opioids: Pharmacology, Abuse, and Addiction

A brief history of opioids and the evolution of concepts associated with substance use disorders
Silvia L. CruzandClaudia Rafful
2. The two sides of opioid use: Unmet needs of opioids for pain management and the role of opioids in substance use disorders
María Elena Medina-Mora, Raúl Martín-del-Campo, Nayely V. Salazar-Trujillo, Hilda Dávila, Clara Fleiz, and Jorge Villatoro