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  3. Acute Promyelocytic Leukemia: Molecular Genetics, Mouse Models and Targeted Therapy

Acute Promyelocytic Leukemia: Molecular Genetics, Mouse Models and Targeted Therapy

Posted By: DZ123
Date: 27 Dec 2019 09:12:02
Acute Promyelocytic Leukemia: Molecular Genetics, Mouse Models and Targeted Therapy

Pier Paolo Pandolfi, Peter K. Vogt, "Acute Promyelocytic Leukemia: Molecular Genetics, Mouse Models and Targeted Therapy"
English | 2007 | ISBN: 3540345922 | PDF | pages: 276 | 2.4 mb

Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development  of targeted therapy.
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